GCM1 rabbit pAb
- Catalog No.:YT6575
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- GCM1
- Fields:
- >>Parathyroid hormone synthesis, secretion and action
- Gene Name:
- GCM1 GCMA
- Protein Name:
- GCM1
- Human Gene Id:
- 8521
- Human Swiss Prot No:
- Q9NP62
- Mouse Gene Id:
- 14531
- Mouse Swiss Prot No:
- P70348
- Rat Gene Id:
- 29394
- Rat Swiss Prot No:
- Q9Z288
- Immunogen:
- Synthesized peptide derived from human GCM1 AA range: 298-348
- Specificity:
- This antibody detects endogenous levels of GCM1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 48kD
- Background:
- This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008],
- Function:
- function:Transcription factor that is necessary for placental development. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer.,similarity:Contains 1 GCM DNA-binding domain.,tissue specificity:Placenta specific.,
- Subcellular Location:
- Nucleus .
- Expression:
- Highly expressed in the placenta (PubMed:10542267). Expressed in trophoblast cells of the villi (PubMed:27917469).
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night