VIP1 rabbit pAb
- Catalog No.:YT6569
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- VIP1
- Fields:
- >>Phosphatidylinositol signaling system
- Gene Name:
- PPIP5K1 HISPPD2A IP6K IPS1 KIAA0377 VIP1
- Protein Name:
- VIP1
- Human Gene Id:
- 9677
- Human Swiss Prot No:
- Q6PFW1
- Mouse Gene Id:
- 327655
- Mouse Swiss Prot No:
- A2ARP1
- Rat Swiss Prot No:
- P0C644
- Immunogen:
- Synthesized peptide derived from human VIP1 AA range: 1350-1400
- Specificity:
- This antibody detects endogenous levels of VIP1 at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 158kD
- Background:
- This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.[provided by RefSeq, Jun 2010],
- Function:
- catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,caution:Although related to histidine acid phosphatases, it lacks the conserved active sites, suggesting that it has no phosphatase activity.,function:Bifunctional inositol kinase that catalyzes the formation of diphosphoinositol pentakisphosphate (InsP7 or PP-InsP5) and bi-diphosphoinositol tetrakisphosphate (InsP8 or PP2-InsP4). Converts inositolitol hexakisphosphate (InsP6) to InsP7. Also able to convert InsP7 to InsP8. Probably specifically mediates
- Subcellular Location:
- Cytoplasm, cytosol . Cell membrane . Relocalizes to the plasma membrane upon activation of the PtdIns 3-kinase pathway. .
- Expression:
- Widely expressed, with a higher expression in skeletal muscle, heart and brain.
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night