PEF1 rabbit pAb

    • Catalog No.:YT6567
    • Applications:WB;IHC
    • Reactivity:Human;Mouse;Rat
      • Target:
      • PEF1
      • Gene Name:
      • PEF1 ABP32 UNQ1845/PRO3573
      • Protein Name:
      • PEF1
      • Human Swiss Prot No:
      • Q9UBV8
      • Mouse Swiss Prot No:
      • Q8BFY6
      • Immunogen:
      • Synthesized peptide derived from human PEF1 AA range: 109-159
      • Specificity:
      • This antibody detects endogenous levels of PEF1 at Human/Mouse/Rat
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000;IHC 1:50-300
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 31kD
      • Background:
      • This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. The encoded protein has been shown to form a heterodimer with the programmed cell death 6 gene product and may modulate its function in Ca(2+) signaling. Alternative splicing results in multiple transcript variants and a pseudogene has been identified on chromosome 1.[provided by RefSeq, May 2010],
      • Function:
      • similarity:Contains 5 EF-hand domains.,subcellular location:Membrane-associated in the presence of Ca(2+).,subunit:Heterodimer; heterodimerizes with PDCD6/ALG2. Dissociates from PDCD6/ALG2 in presence of Ca(2+).,
      • Subcellular Location:
      • Cytoplasm . Endoplasmic reticulum . Membrane ; Peripheral membrane protein . Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein . Membrane-associated in the presence of Ca(2+) (PubMed:11278427). Localizes to endoplasmic reticulum exit site (ERES) (By similarity). .
      • Products Images
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).