ACADL rabbit pAb
- Catalog No.:YT6498
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- ACADL
- Fields:
- >>Fatty acid degradation;>>Metabolic pathways;>>Fatty acid metabolism;>>PPAR signaling pathway
- Gene Name:
- ACADL
- Protein Name:
- ACADL
- Human Gene Id:
- 33
- Human Swiss Prot No:
- P28330
- Mouse Gene Id:
- 11363
- Mouse Swiss Prot No:
- P51174
- Rat Gene Id:
- 25287
- Rat Swiss Prot No:
- P15650
- Immunogen:
- Synthesized peptide derived from human ACADL AA range: 258-308
- Specificity:
- This antibody detects endogenous levels of ACADL at Human/Mouse/Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 47kD
- Background:
- The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008],
- Function:
- catalytic activity:Acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.,cofactor:FAD.,disease:Impaired ACADL activity results in non-ketotic hypoglycemia, hypotonia, muscle weakness and episodes of cardiorespiratory arrest associated with fasting [MIM:201460].,miscellaneous:A number of straight-chain acyl-CoA dehydrogenases of different substrate specificities are present in mammalian tissues.,pathway:Lipid metabolism; mitochondrial fatty acid beta-oxidation.,similarity:Belongs to the acyl-CoA dehydrogenase family.,subunit:Homotetramer.,
- Subcellular Location:
- Mitochondrion matrix .
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- Antibody-FAQs
- Products Images
- Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night