INT8 rabbit pAb

    • Catalog No.:YT6367
    • Applications:WB
    • Reactivity:Human;Mouse
      • Target:
      • INT8
      • Gene Name:
      • INTS8 C8orf52
      • Protein Name:
      • INT8
      • Human Swiss Prot No:
      • Q75QN2
      • Mouse Swiss Prot No:
      • Q80V86
      • Immunogen:
      • Synthesized peptide derived from human INT8 AA range: 346-396
      • Specificity:
      • This antibody detects endogenous levels of INT8 at Human/Mouse
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Molecular Weight(Da):
      • 109kD
      • Background:
      • This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012],
      • Function:
      • function:Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.,similarity:Contains 4 TPR repeats.,subunit:Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.,
      • Subcellular Location:
      • Nucleus .
      • Products Images
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night