• Target：
• PIGL

• Fields：
• >>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways

• Gene Name：
• PIGL

• Protein Name：
• PIGL

• Human Gene Id：
• 9487

• Human Swiss Prot No：
• Q9Y2B2

• Mouse Gene Id：
• 327942

• Mouse Swiss Prot No：
• Q5SX19

• Rat Gene Id：
• 192263

• Rat Swiss Prot No：
• O35790

• Immunogen：
• Synthesized peptide derived from human PIGL AA range: 77-127

• Specificity：
• This antibody detects endogenous levels of PIGL at Human/Mouse/Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000; IF ICC 1:50-200;ELISA 1:2000-20000;IHC 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Molecular Weight(Da)：
• 28kD

• Background：
• This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum. [provided by RefSeq, Jul 2008],

• Function：
• catalytic activity:6-(N-acetyl-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate.,function:Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGL family.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Single-pass membrane protein .

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