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- T2H2L rabbit pAb
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T2H2L rabbit pAb
- Catalog No.:YT6341
- Applications:WB
- Reactivity:Human
- Fields:
- >>Basal transcription factors;>>Nucleotide excision repair;>>Viral carcinogenesis
- Gene Name:
- GTF2H2C; GTF2H2D
- Immunogen:
- Synthesized peptide derived from human T2H2L AA range: 275-325
- Specificity:
- This antibody detects endogenous levels of T2H2L at Human
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Molecular Weight(Da):
- 43kD
- Function:
- alternative products:A number of isoforms may be produced. The isoforms may be also produced by incomplete gene duplication,function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.,similarity:Belongs to the GTF2H2 family.,similarity:Contains 1 VWFA domain.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with XPB, XPD, GTF2H1 and GTF2H3.,tissue specificity:Widely expressed, with higher express
- Subcellular Location:
- Nucleus .
![](/uploadfiles/PIC/YT6341wb-2019.jpg)
- Western blot analysis of lysates from Jurkat cells, primary antibody was diluted at 1:1000, 4°over night