• Target：
• LWS

• Fields：
• >>PPAR signaling pathway;>>Th17 cell differentiation;>>Thyroid hormone signaling pathway;>>Adipocytokine signaling pathway;>>Parathyroid hormone synthesis, secretion and action;>>Pathways in cancer;>>Transcriptional misregulation in cancer;>>Chemical carcinogenesis - receptor activation;>>Thyroid cancer;>>Small cell lung cancer;>>Non-small cell lung cancer;>>Gastric cancer;>>Lipid and atherosclerosis

• Gene Name：
• RXRG NR2B3

• Protein Name：
• LWS

• Human Gene Id：
• 6258

• Human Swiss Prot No：
• P48443

• Mouse Gene Id：
• 20183

• Mouse Swiss Prot No：
• P28705

• Immunogen：
• Synthesized peptide derived from human LWS. at AA range: 380-420

• Specificity：
• This antibody detects endogenous levels of LWS

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000, ELISA 1:10000-20000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma)

• Observed Band(KD)：
• 50kD

• Background：
• retinoid X receptor gamma(RXRG) Homo sapiens This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010],

• Function：
• caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,function:Nuclear hormone receptor. Involved in the retinoic acid response pathway. Binds 9-cis retinoic acid (9C-RA).,similarity:Belongs to the nuclear hormone receptor family. NR2 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,

• Subcellular Location：
• Nucleus . Cytoplasm .

• Expression：
• Expressed in aortic endothelial cells (at protein level).

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