SCGF Polyclonal Antibody

    • Catalog No.:YT5719
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • SCGF
      • Gene Name:
      • CLEC11A
      • Protein Name:
      • C-type lectin domain family 11 member A
      • Human Gene Id:
      • 6320
      • Human Swiss Prot No:
      • Q9Y240
      • Mouse Swiss Prot No:
      • O88200
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from the N-terminal region of human CLEC11A. AA range:1-50
      • Specificity:
      • SCGF Polyclonal Antibody detects endogenous levels of SCGF protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CLEC11A;CLECSF3;LSLCL;SCGF;C-type lectin domain family 11 member A;C-type lectin superfamily member 3;Lymphocyte secreted C-type lectin;Stem cell growth factor;p47
      • Observed Band(KD):
      • 30kD
      • Background:
      • This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008],
      • Function:
      • developmental stage:In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.,function:Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.,online information:Stem cell growth factor,PTM:O-glycosylated. Probably sulfated on the O-glycans.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.,
      • Subcellular Location:
      • Cytoplasm . Secreted .
      • Expression:
      • Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
      • Products Images
      • Western blot analysis of MOUSE-SPLEEN RAT-SPLEEN using CLEC11A antibody. Antibody was diluted at 1:2000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded human-skin, antibody was diluted at 1:100