• Target：
• CD229

• Gene Name：
• LY9

• Protein Name：
• T-lymphocyte surface antigen Ly-9

• Human Gene Id：
• 4063

• Human Swiss Prot No：
• Q9HBG7

• Mouse Gene Id：
• 17085

• Mouse Swiss Prot No：
• Q01965

• Immunogen：
• The antiserum was produced against synthesized peptide derived from the Internal region of human LY9. AA range:261-310

• Specificity：
• CD229 Polyclonal Antibody detects endogenous levels of CD229 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LY9;CDABP0070;T-lymphocyte surface antigen Ly-9;Cell surface molecule Ly-9;Lymphocyte antigen 9;CD229

• Observed Band(KD)：
• 72kD

• Background：
• LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM, Mar 2008],

• Function：
• alternative products:Experimental confirmation may be lacking for some isoforms,function:May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,

• Subcellular Location：
• Membrane; Single-pass type I membrane protein. Cell membrane .

• Expression：
• Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.

SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome INTERNATIONAL IMMUNOPHARMACOLOGY Peini Hu IHC Human 1:50 Labial gland tissue

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