CD107a Polyclonal Antibody

    • Catalog No.:YT5260
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • CD107a
      • Fields:
      • >>Autophagy - animal;>>Lysosome;>>Phagosome;>>Tuberculosis
      • Gene Name:
      • LAMP1
      • Protein Name:
      • Lysosome-associated membrane glycoprotein 1
      • Human Gene Id:
      • 3916
      • Human Swiss Prot No:
      • P11279
      • Mouse Swiss Prot No:
      • P11438
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from the Internal region of human LAMP1. AA range:211-260
      • Specificity:
      • CD107a Polyclonal Antibody detects endogenous levels of CD107a protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • LAMP1;Lysosome-associated membrane glycoprotein 1;LAMP-1;Lysosome-associated membrane protein 1;CD107 antigen-like family member A;CD107a
      • Observed Band(KD):
      • 120kD
      • Background:
      • The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,
      • Subcellular Location:
      • Cell membrane ; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Cytolytic granule membrane ; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). .
      • Expression:
      • Brain,Liver,Pancreas,Placenta,Plasma,Testis,
      • Products Images
      • Western Blot analysis of L929 cells using CD107a Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Western blot analysis of lysate from L929 cells, using LAMP1 Antibody.