• Target：
• Uba5

• Gene Name：
• UBA5

• Protein Name：
• Ubiquitin-like modifier-activating enzyme 5

• Human Gene Id：
• 79876

• Human Swiss Prot No：
• Q9GZZ9

• Mouse Gene Id：
• 66663

• Mouse Swiss Prot No：
• Q8VE47

• Rat Gene Id：
• 300968

• Rat Swiss Prot No：
• Q5M7A4

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human UBA5. AA range:281-330

• Specificity：
• Uba5 Polyclonal Antibody detects endogenous levels of Uba5 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• UBA5;UBE1DC1;Ubiquitin-like modifier-activating enzyme 5;Ubiquitin-activating enzyme 5;ThiFP1;UFM1-activating enzyme;Ubiquitin-activating enzyme E1 domain-containing protein 1

• Observed Band(KD)：
• 45kD

• Background：
• This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1. [provided by RefSeq, Feb 2016],

• Function：
• function:E1-like enzyme which activates UFM1.,similarity:Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.,

• Subcellular Location：
• Cytoplasm . Nucleus . Endoplasmic reticulum membrane . Golgi apparatus . Localizes mainly in the cytoplasm, while it localizes to the nucleus in presence of SUMO2 (PubMed:18442052). Interaction with GABARAPL2 promotes localization to the endoplasmic reticulum membrane (PubMed:30990354). .

• Expression：
• Widely expressed.

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