• Target：
• PIG-X

• Fields：
• >>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways

• Gene Name：
• PIGX

• Protein Name：
• Phosphatidylinositol-glycan biosynthesis class X protein

• Human Gene Id：
• 54965

• Human Swiss Prot No：
• Q8TBF5

• Mouse Swiss Prot No：
• Q99LV7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human PIGX. AA range:183-232

• Specificity：
• PIG-X Polyclonal Antibody detects endogenous levels of PIG-X protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• PIGX;Phosphatidylinositol-glycan biosynthesis class X protein;PIG-X

• Observed Band(KD)：
• 26kD

• Background：
• This gene encodes a type I transmembrane protein in the endoplasmic reticulum (ER). The protein is an essential component of glycosylphosphatidylinositol-mannosyltransferase I, which transfers the first of the four mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Studies in rat indicate that the protein is translated from a non-AUG translation initiation site. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

• Function：
• function:Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,PTM:N-glycosylated.,sequence caution:Unusual initiator. The initiator methionine is coded by a non-canonical CTG leucine codon.,similarity:Belongs to the PIGX family.,subunit:Interacts with PIGM.,

• Subcellular Location：
• Endoplasmic reticulum membrane ; Single-pass type I membrane protein .

• Expression：
• Brain,

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