p39 Polyclonal Antibody

    • Catalog No.:YT3515
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • p39
      • Gene Name:
      • CDK5R2
      • Protein Name:
      • Cyclin-dependent kinase 5 activator 2
      • Human Gene Id:
      • 8941
      • Human Swiss Prot No:
      • Q13319
      • Mouse Swiss Prot No:
      • O35926
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human CDK5R2. AA range:81-130
      • Specificity:
      • p39 Polyclonal Antibody detects endogenous levels of p39 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • CDK5R2;NCK5AI;Cyclin-dependent kinase 5 activator 2;CDK5 activator 2;Cyclin-dependent kinase 5 regulatory subunit 2;p39;p39I
      • Observed Band(KD):
      • 40kD
      • Background:
      • The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Activator of CDK5/TPKII.,similarity:Belongs to the cyclin-dependent kinase 5 activator family.,subunit:Heterodimer of a catalytic subunit and a regulatory subunit.,tissue specificity:Brain and neuron specific.,
      • Subcellular Location:
      • Cell membrane ; Lipid-anchor ; Cytoplasmic side .
      • Expression:
      • Brain and neuron specific.
      • Products Images
      • Western Blot analysis of various cells using p39 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
      • Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Western blot analysis of lysates from HUVEC cells, using CDK5R2 Antibody. The lane on the right is blocked with the synthesized peptide.