• Target：
• NPY1-R

• Fields：
• >>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction;>>Regulation of lipolysis in adipocytes

• Gene Name：
• NPY1R

• Protein Name：
• Neuropeptide Y receptor type 1

• Human Gene Id：
• 4886

• Human Swiss Prot No：
• P25929

• Mouse Gene Id：
• 18166

• Mouse Swiss Prot No：
• Q04573

• Rat Swiss Prot No：
• P21555

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human NPY1R. AA range:221-270

• Specificity：
• NPY1-R Polyclonal Antibody detects endogenous levels of NPY1-R protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• NPY1R;NPYR;NPYY1;Neuropeptide Y receptor type 1;NPY1-R

• Observed Band(KD)：
• 48kD

• Background：
• This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013],

• Function：
• function:Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.,similarity:Belongs to the G-protein coupled receptor 1 family.,

• Subcellular Location：
• Cell membrane; Multi-pass membrane protein.

• Expression：
• Blood,Brain,Pancreas,Testis,

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