• Target：
• LIR-6

• Fields：
• >>Osteoclast differentiation;>>B cell receptor signaling pathway

• Gene Name：
• LILRA1

• Protein Name：
• Leukocyte immunoglobulin-like receptor subfamily A member 1

• Human Gene Id：
• 11024

• Human Swiss Prot No：
• O75019

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human LILRA1. AA range:53-102

• Specificity：
• LIR-6 Polyclonal Antibody detects endogenous levels of LIR-6 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• LILRA1;LIR6;Leukocyte immunoglobulin-like receptor subfamily A member 1;CD85 antigen-like family member I;Leukocyte immunoglobulin-like receptor 6;LIR-6;CD antigen CD85i

• Observed Band(KD)：
• 53kD

• Background：
• This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],

• Function：
• function:May act as receptor for class I MHC antigens.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected in monocytes and B-cells.,

• Subcellular Location：
• Membrane; Single-pass type I membrane protein.

• Expression：
• Detected in monocytes and B-cells.

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