IFITM3 Polyclonal Antibody

  • Catalog No.:YT2277
  • Applications:WB;IF;ELISA
  • Reactivity:Human;Rat;Mouse;
    • Target:
    • IFITM3
    • Gene Name:
    • IFITM3
    • Protein Name:
    • Interferon-induced transmembrane protein 3
    • Human Swiss Prot No:
    • Q01628
    • Mouse Swiss Prot No:
    • Q9CQW9
    • Immunogen:
    • The antiserum was produced against synthesized peptide derived from human IFM3. AA range:1-50
    • Specificity:
    • IFITM3 Polyclonal Antibody detects endogenous levels of IFITM3 protein.
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • IFITM3;Interferon-induced transmembrane protein 3;Dispanin subfamily A member 2b;DSPA2b;Interferon-inducible protein 1-8U
    • Observed Band(KD):
    • 15kD
    • Background:
    • The protein encoded by this gene is an interferon-induced membrane protein that helps confer immunity to influenza A H1N1 virus, West Nile virus, and dengue virus. Two transcript variants, only one of them protein-coding, have been found for this gene. Another variant encoding an N-terminally truncated isoform has been reported, but the full-length nature of this variant has not been determined. [provided by RefSeq, May 2012],
    • Function:
    • induction:By alpha and gamma interferons.,similarity:Belongs to the CD225 family.,
    • Subcellular Location:
    • Cell membrane ; Single-pass type II membrane protein . Late endosome membrane ; Single-pass type II membrane protein . Early endosome membrane ; Single-pass type II membrane protein. Lysosome membrane ; Single-pass type II membrane protein . Cytoplasm, perinuclear region . Co-localizes with BRI3 isoform 1 at the perinuclear region. .
    • Expression:
    • Brain,Cervix,Vascular endothelial cell,