• Target：
• HORMAD1

• Gene Name：
• HORMAD1

• Protein Name：
• HORMA domain-containing protein 1

• Human Gene Id：
• 84072

• Human Swiss Prot No：
• Q86X24

• Mouse Swiss Prot No：
• Q9D5T7

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human HORMAD1. AA range:321-370

• Specificity：
• HORMAD1 Polyclonal Antibody detects endogenous levels of HORMAD1 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• HORMAD1;NOHMA;HORMA domain-containing protein 1;Cancer/testis antigen 46;CT46;Newborn ovary HORMA protein

• Observed Band(KD)：
• 45kD

• Background：
• This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],

• Function：
• similarity:Contains 1 HORMA domain.,tissue specificity:Testis-specific. Over-expressed in carcinomas.,

• Subcellular Location：
• Nucleus . Chromosome . Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity). .

• Expression：
• Testis-specific. Over-expressed in carcinomas.

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