Connexin 31.3 Polyclonal Antibody

    • Catalog No.：YT1042
    • Applications：WB;ELISA
    • Reactivity：Human;Mouse
      • Target：
      • Connexin 31.3
      • Gene Name：
      • GJC3
      • Protein Name：
      • Gap junction gamma-3 protein
      • Human Swiss Prot No：
      • Q8NFK1
      • Mouse Swiss Prot No：
      • Q921C1
      • Immunogen：
      • The antiserum was produced against synthesized peptide derived from human GJC3. AA range:151-200
      • Specificity：
      • Connexin 31.3 Polyclonal Antibody detects endogenous levels of Connexin 31.3 protein.
      • Formulation：
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source：
      • Polyclonal, Rabbit,IgG
      • Dilution：
      • WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
      • Purification：
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration：
      • 1 mg/ml
      • Storage Stability：
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name：
      • GJC3;GJE1;Gap junction gamma-3 protein;Connexin-30.2;Cx30.2;Connexin-31.3;Cx31.3;Gap junction epsilon-1 protein
      • Observed Band(KD)：
      • 28kD
      • Background：
      • This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010],
      • Function：
      • function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038 expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.,
      • Subcellular Location：
      • Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .
      • Expression：
      • CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.
      • Products Images
      • Western blot analysis of the lysates from K562 cells using GJC3 antibody.

      Attributes

      • Code：
      • YT1042
      • Size
      • 40μL / 100μL / 200μL
      • Price$：
      • 150 / 280 / 450
      • Delivery：
      • 2024-11-24
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