COL14A1 Polyclonal Antibody
- Catalog No.:YT1012
- Applications:IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- COL14A1
- Fields:
- >>Protein digestion and absorption
- Gene Name:
- COL14A1
- Protein Name:
- Collagen alpha-1(XIV) chain
- Human Gene Id:
- 7373
- Human Swiss Prot No:
- Q05707
- Mouse Swiss Prot No:
- Q80X19
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human N-ternal Collagen XIV alpha1. AA range:71-120
- Specificity:
- COL14A1 Polyclonal Antibody detects endogenous levels of COL14A1 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- COL14A1;UND;Collagen alpha-1(XIV) chain;Undulin
- Molecular Weight(Da):
- 194kD
- Background:
- This gene encodes the alpha chain of type XIV collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XIV collagen interacts with the fibril surface and is involved in the regulation of fibrillogenesis. [provided by RefSeq, Jan 2013],
- Function:
- function:Plays an adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors.,PTM:Lysines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in all cases and bind carbohydrates.,PTM:May contain numerous cysteine residues involved in inter- and intramolecular disulfide bonding.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,similarity:Contains 1 TSP N-terminal (TSPN) domain.,similarity:
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix .
- Expression:
- Brain,Liver,Muscle,PNS,Testis,
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- Antibody-FAQs
- Products Images
- Immunofluorescence analysis of HeLa cells, using Collagen XIV alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.
- Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Collagen XIV alpha1 Antibody. The picture on the right is blocked with the synthesized peptide.