Carbonic Anhydrase 9 (PT0209R) PT® Rabbit mAb

    • Catalog No.:YM8132
    • Applications:WB;IHC;IF;IP;ELISA
    • Reactivity:Human; Mouse; Rat;
      • Target:
      • CA IX
      • Fields:
      • >>Nitrogen metabolism;>>Metabolic pathways
      • Gene Name:
      • CA9
      • Protein Name:
      • Carbonic anhydrase 9
      • Human Gene Id:
      • 768
      • Human Swiss Prot No:
      • Q16790
      • Mouse Swiss Prot No:
      • Q8VHB5
      • Specificity:
      • endogenous
      • Formulation:
      • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
      • Source:
      • Monoclonal, rabbit, IgG, Kappa
      • Dilution:
      • IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
      • Purification:
      • Protein A
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1
      • Molecular Weight(Da):
      • 49kD
      • Observed Band(KD):
      • 49kD
      • Function:
      • catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.,induction:By hypoxia.,PTM:Asn-346 bears high-mannose type glycan structures.,similarity:Belongs to the alpha-carbonic anhydrase family.,subcellular location:Found on the surface microvilli and in the nucleus, particularly in nucleolus.,subunit:Forms oligomers linked by disulfide bonds.,tissue specificity:Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.,
      • Subcellular Location:
      • Membranous
      • Expression:
      • Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
      • Products Images
      • Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Carbonic Anhydrase 9 (PT0209R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: PC-12 Lane 2: U-14 Lane 3: Rat womb Predicted band size: 49kDa Observed band size: 49kDa
      • Human tonsil was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody
      • Rat stomach was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody
      • Human colon carcinoma was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody
      • Human stomach was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody