Carbonic Anhydrase 9 (PT0209R) PT® Rabbit mAb
- Catalog No.:YM8132
- Applications:WB;IHC;IF;IP;ELISA
- Reactivity:Human; Mouse; Rat;
- Target:
- CA IX
- Fields:
- >>Nitrogen metabolism;>>Metabolic pathways
- Gene Name:
- CA9
- Protein Name:
- Carbonic anhydrase 9
- Human Gene Id:
- 768
- Human Swiss Prot No:
- Q16790
- Mouse Gene Id:
- 230099
- Mouse Swiss Prot No:
- Q8VHB5
- Specificity:
- endogenous
- Formulation:
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source:
- Monoclonal, rabbit, IgG, Kappa
- Dilution:
- IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
- Purification:
- Protein A
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- G250; MN; Carbonic anhydrase 9; Carbonate dehydratase IX; Carbonic anhydrase IX; CA-IX; CAIX; Membrane antigen MN; P54/58N; Renal cell carcinoma-associated antigen G250; RCC-associated antigen G250; pMW1
- Molecular Weight(Da):
- 49kD
- Observed Band(KD):
- 49kD
- Function:
- catalytic activity:H(2)CO(3) = CO(2) + H(2)O.,cofactor:Zinc.,function:Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.,induction:By hypoxia.,PTM:Asn-346 bears high-mannose type glycan structures.,similarity:Belongs to the alpha-carbonic anhydrase family.,subcellular location:Found on the surface microvilli and in the nucleus, particularly in nucleolus.,subunit:Forms oligomers linked by disulfide bonds.,tissue specificity:Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.,
- Subcellular Location:
- Membranous
- Expression:
- Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
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- Antibody-FAQs
- Products Images
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Carbonic Anhydrase 9 (PT0209R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: PC-12 Lane 2: U-14 Lane 3: Rat womb Predicted band size: 49kDa Observed band size: 49kDa
- Human tonsil was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody
- Rat stomach was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody
- Human colon carcinoma was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody
- Human stomach was stained with Anti-Carbonic Anhydrase 9 (PT0209R) rabbit antibody