Stromal Interaction Molecule 1 (PT0172R) PT® Rabbit mAb
- Catalog No.：YM8105
- Applications：WB;IHC;IF;IP;ELISA
- Reactivity：Human; Mouse; Rat;
- Protein Name：
- STIM1 GOK
- Sequence：
- Stromal interaction molecule 1
- Human Gene Id：
- 6786
- Human Swiss Prot No：
- Q13586
- Mouse Gene Id：
- 20866
- Mouse Swiss Prot No：
- P70302
- Rat Gene Id：
- 361618
- Rat Swiss Prot No：
- P84903
- Specificity：
- endogenous
- Formulation：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source：
- Monoclonal, rabbit, IgG, Kappa
- Dilution：
- IHC 1:200-1:1000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
- Purification：
- Protein A
- Storage Stability：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name：
- Stromal interaction molecule 1
- Molecular Weight(Da)：
- 77kD
- Observed Band(KD)：
- 77kD
- Function：
- Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch .
- Subcellular Location：
- Membrane
- Expression：
- Ubiquitously expressed in various human primary cells and tumor cell lines.
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- Antibody-FAQs
- Products Images
- Mouse spleen was stained with anti-Stromal Interaction Molecule 1 (PT0172R) rabbit antibody
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Stromal Interaction Molecule 1 (PT0172R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: C6 Lane 2: Hela Lane 3: U-14 Lane 4: A20 Predicted band size: 77kDa Observed band size: 77kDa
- Human breast was stained with anti-Stromal Interaction Molecule 1 (PT0172R) rabbit antibody
- Human spleen was stained with anti-Stromal Interaction Molecule 1 (PT0172R) rabbit antibody
