CDC37 (phospho Ser13) (PT0060R) PT® Rabbit mAb
- Catalog No.：YM8031
- Applications：WB;IHC;IF;IP;ELISA
- Reactivity：Human; Mouse; Rat;
- Target：
- Cdc37
- Fields：
- >>PI3K-Akt signaling pathway
- Gene Name：
- CDC37
- Protein Name：
- Hsp90 co-chaperone Cdc37
- Human Gene Id：
- 11140
- Human Swiss Prot No：
- Q16543
- Mouse Gene Id：
- 12539
- Mouse Swiss Prot No：
- Q61081
- Rat Gene Id：
- 114562
- Rat Swiss Prot No：
- Q63692
- Specificity：
- endogenous
- Formulation：
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source：
- Monoclonal, rabbit, IgG, Kappa
- Dilution：
- IHC 1:400-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200
- Purification：
- Protein A
- Storage Stability：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name：
- CDC37;CDC37A;Hsp90 co-chaperone Cdc37;Hsp90 chaperone protein kinase-targeting subunit;p50Cdc37
- Molecular Weight(Da)：
- 44kD
- Observed Band(KD)：
- 44kD
- Background：
- The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008],
- Function：
- function:Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.,PTM:Constitutively sumoylated by UBE2I.,similarity:Belongs to the CDC37 family.,subunit:Forms a complex with Hsp90. Interacts with AR, CDK4, CDK6, EIF2AK1 and RB1.,
- Subcellular Location：
- Cytoplasm
- Expression：
- Lymph,Placenta,
- June 19-2018
- WESTERN IMMUNOBLOTTING PROTOCOL
- June 19-2018
- IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL
- June 19-2018
- IMMUNOFLUORESCENCE PROTOCOL
- September 08-2020
- FLOW-CYTOMEYRT-PROTOCOL
- May 20-2022
- Cell-Based ELISA│解您多样本WB检测之困扰
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN
- July 13-2018
- CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN
- July 13-2018
- Antibody-FAQs
- Products Images
- Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-CDC37 (phospho Ser13) (PT0060R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: PC-12 Lane 2: HEK293 Lane 3: Hela Lane 4: NIH-3T3 Predicted band size: 44kDa Observed band size: 44kDa
- Human brain was stained with Anti-CDC37 (phospho Ser13) (PT0060R) rabbit antibody
- Mouse brain was stained with Anti-CDC37 (phospho Ser13) (PT0060R) rabbit antibody
- Rat brain was stained with Anti-CDC37 (phospho Ser13) (PT0060R) rabbit antibody
