CD37 Monoclonal Antibody
- Catalog No.:YM0121
- Applications:IF;ELISA
- Reactivity:Human;Mouse
- Target:
- CD37
- Fields:
- >>Hematopoietic cell lineage
- Gene Name:
- CD37
- Protein Name:
- Leukocyte antigen CD37
- Human Gene Id:
- 951
- Human Swiss Prot No:
- P11049
- Mouse Gene Id:
- 12493
- Mouse Swiss Prot No:
- Q61470
- Immunogen:
- Purified recombinant fragment of CD37 expressed in E. Coli.
- Specificity:
- CD37 Monoclonal Antibody detects endogenous levels of CD37 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Monoclonal, Mouse
- Dilution:
- IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
- Purification:
- Affinity purification
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- CD37;TSPAN26;Leukocyte antigen CD37;Tetraspanin-26;Tspan-26;CD antigen CD37
- References:
- 1. J Immunol. 2004 Mar 1;172(5):2953-61.
2. J Immunol. 2007 Jan 1;178(1):154-62.
- Background:
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
- Function:
- similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:B-lymphocytes.,
- Subcellular Location:
- Membrane; Multi-pass membrane protein.
- Expression:
- B-lymphocytes.
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- Products Images
- Confocal immunofluorescence analysis of methanol-fixed BCBL-1 (left) and L1210 (right) cells using CD37 Monoclonal Antibody (green), showing membrane localization. Blue: DRAQ5 fluorescent DNA dye.