• Target：
• CD34

• Fields：
• >>Cell adhesion molecules;>>Hematopoietic cell lineage

• Gene Name：
• CD34

• Protein Name：
• Hematopoietic progenitor cell antigen CD34

• Human Gene Id：
• 947

• Human Swiss Prot No：
• P28906

• Mouse Swiss Prot No：
• Q64314

• Immunogen：
• Purified recombinant fragment of CD34 expressed in E. Coli.

• Specificity：
• CD34 Monoclonal Antibody detects endogenous levels of CD34 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Monoclonal, Mouse

• Dilution：
• WB 1:500 - 1:2000. IHC 1:200 - 1:1000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

• Purification：
• Affinity purification

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• CD34;Hematopoietic progenitor cell antigen CD34;CD antigen CD34

• Molecular Weight(Da)：
• 41kD

• References：
• 1. Sho E., et al. Arterioscler Thromb Vasc Biol. 2004: 24: 1916-21.
  2. Satterthwaite, A.B.,et al. Genomics.1992:12:788-794.
  3. Krause, D.S.,et al. 1994. Blood.84: 691-701.

• Background：
• The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],

• Function：
• alternative products:Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,function:Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tiss

• Subcellular Location：
• Membrane; Single-pass type I membrane protein.

• Expression：
• Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.

• June 19-2018
• WESTERN IMMUNOBLOTTING PROTOCOL

• June 19-2018
• IMMUNOHISTOCHEMISTRY-PARAFFIN PROTOCOL

• June 19-2018
• IMMUNOFLUORESCENCE PROTOCOL

• September 08-2020
• FLOW-CYTOMEYRT-PROTOCOL

• May 20-2022
• Cell-Based ELISA│解您多样本WB检测之困扰

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-ACETYL-PROTEIN

• July 13-2018
• CELL-BASED-ELISA-PROTOCOL-FOR-PHOSPHO-PROTEIN

• July 13-2018
• CELL-BASED-COLORIMETRIC-ELISA-PROTOCOL-FOR-TOTAL-PROTEIN

• July 13-2018
• Antibody-FAQs