• Target：
• ACSL4

• Fields：
• >>Fatty acid biosynthesis;>>Fatty acid degradation;>>Metabolic pathways;>>Fatty acid metabolism;>>PPAR signaling pathway;>>Peroxisome;>>Ferroptosis;>>Thermogenesis;>>Adipocytokine signaling pathway

• Gene Name：
• ACSL4 ACS4 FACL4 LACS4

• Protein Name：
• ACSL4

• Human Gene Id：
• 2182

• Human Swiss Prot No：
• O60488

• Mouse Gene Id：
• 50790

• Mouse Swiss Prot No：
• Q9QUJ7

• Rat Gene Id：
• 113976

• Rat Swiss Prot No：
• O35547

• Immunogen：
• Synthesized peptide derived from human ACSL4

• Specificity：
• This antibody detects endogenous levels of ACSL4 at Human, Mouse,Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4)

• Observed Band(KD)：
• 75kD

• Subcellular Location：
• Mitochondrion outer membrane ; Single-pass type III membrane protein . Peroxisome membrane ; Single-pass type III membrane protein . Microsome membrane ; Single-pass type III membrane protein . Endoplasmic reticulum membrane ; Single-pass type III membrane protein . Cell membrane .

Regulation of Fatty Acid Metabolism and Inhibition of Colorectal Cancer Progression by Erchen Decoction Evidence-based Complementary and Alternative Medicine Linghong Liao WB Mouse colorectal tissue

Integration of metabolomics and transcriptomics reveals that Da Chuanxiong Formula improves vascular cognitive impairment via ACSL4/GPX4 mediated ferroptosis JOURNAL OF ETHNOPHARMACOLOGY Tianyu Lou WB Rat brain tissue

Gualou-Xiebai herb pair ameliorate atherosclerosis in HFD-induced ApoE−/− mice and inhibit the ox-LDL-induced injury of HUVECs by regulating the Nrf2-mediated ferroptosis JOURNAL OF ETHNOPHARMACOLOGY Li Zhu WB Human human vascular endothelial cells (HUVECs)

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