TSSK6 rabbit pAb

  • Catalog No.:YT8050
  • Applications:WB
  • Reactivity:Human;Mouse;Rat
    • Target:
    • TSSK6
    • Gene Name:
    • TSSK6 SSTK FKSG82
    • Protein Name:
    • TSSK6
    • Human Swiss Prot No:
    • Q9BXA6
    • Mouse Swiss Prot No:
    • Q925K9
    • Immunogen:
    • Synthesized peptide derived from human TSSK6
    • Specificity:
    • This antibody detects endogenous levels of TSSK6 at Human, Mouse,Rat
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:500-2000
    • Purification:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Testis-specific serine/threonine-protein kinase 6 (TSK-6) (TSSK-6) (Testis-specific kinase 6) (EC 2.7.11.1) (Cancer/testis antigen 72) (CT72) (Serine/threonine-protein kinase SSTK) (Small serine/threonine kinase)
    • Molecular Weight(Da):
    • 33kD
    • Background:
    • This intronless gene encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family. The encoded kinase has a broad expression pattern but is described as testis-specific due to effects on fertility. Male mice which lack the gene encoding a highly similar protein are sterile and have morphologically abnormal sperm. [provided by RefSeq, Jan 2012],
    • Function:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Required for sperm production and function. Plays a role in DNA condensation during postmeiotic chromatin remodeling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the heatshock proteins HSPCB, HSPA8 and HAPA1A. These interactions appear to be required for TSSK6 kinase activity.,tissue specificity:Highly expressed in testis. Expressed at lower levels in human colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.,
    • Subcellular Location:
    • nucleus,cytoplasm,
    • Expression:
    • Highly expressed in testis. Expressed at lower levels in colon, small intestine, ovary, prostate, thymus, spleen and peripheral blood leukocytes.