Rictor rabbit pAb

  • Catalog No.：YT7983
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse;Monkey
    • Target：
    • RICTR
    • Fields：
    • >>mTOR signaling pathway
    • Gene Name：
    • RICTOR KIAA1999
    • Protein Name：
    • RICTR
    • Human Swiss Prot No：
    • Q6R327
    • Mouse Swiss Prot No：
    • Q6QI06
    • Immunogen：
    • Synthesized peptide derived from human RICTR
    • Specificity：
    • This antibody detects endogenous levels of Human,Mouse,Monkey RICTR
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Rapamycin-insensitive companion of mTOR (AVO3 homolog;hAVO3)
    • Molecular Weight(Da)：
    • 188kD
    • Background：
    • RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],
    • Function：
    • function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2.,

    Attributes

    • Code：
    • YT7983
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-11-24
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