AGRP rabbit pAb

  • Catalog No.：YT7903
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse
    • Target：
    • AGRP
    • Fields：
    • >>Adipocytokine signaling pathway
    • Gene Name：
    • AGRP AGRT ART
    • Protein Name：
    • AGRP
    • Human Gene Id：
    • 181
    • Human Swiss Prot No：
    • O00253
    • Mouse Swiss Prot No：
    • P56473
    • Immunogen：
    • Synthesized peptide derived from human AGRP
    • Specificity：
    • This antibody detects endogenous levels of Human AGRP
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Agouti-related protein
    • Molecular Weight(Da)：
    • 15kD
    • Background：
    • disease:Defects in AGRP may be a cause of autosomal dominant obesity [MIM:601665].,domain:The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.,function:Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding.,similarity:Contains 1 agouti domain.,tissue specificity:Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.,
    • Function：
    • cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway, intracellular signaling cascade, behavior, feeding behavior, adult feeding behavior, response to endogenous stimulus, response to hormone stimulus, hormone-mediated signaling, response to organic substance,adult behavior, cellular response to hormone stimulus, eating behavior,
    • Subcellular Location：
    • Secreted . Golgi apparatus lumen .
    • Expression：
    • Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.

    Attributes

    • Code：
    • YT7903
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-07-26
    Order

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