S-100A6 rabbit pAb
- Catalog No.:YT7855
- Applications:WB;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- S100A6
- Gene Name:
- S100A6 CACY
- Protein Name:
- S-100A6
- Human Gene Id:
- 6277
- Human Swiss Prot No:
- P06703
- Mouse Gene Id:
- 20200
- Mouse Swiss Prot No:
- P14069
- Rat Gene Id:
- 85247
- Rat Swiss Prot No:
- P05964
- Immunogen:
- Synthesized peptide derived from human S-100A6 AA range: 21-70
- Specificity:
- This antibody detects endogenous levels of Human S-100A6
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:1000-2000 ELISA 1:5000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Protein S100-A6 (Calcyclin;Growth factor-inducible protein 2A9;MLN 4;Prolactin receptor-associated protein;PRA;S100 calcium-binding protein A6)
- Molecular Weight(Da):
- 10kD
- Background:
- S100 calcium binding protein A6(S100A6) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008],
- Function:
- induction:Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.,miscellaneous:This protein co-purified with the prolactin receptor.,PTM:The N-terminus is blocked.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer, antiparallel. Interacts with SUGT1.,
- Subcellular Location:
- Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
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