CXCL2 rabbit pAb

  • Catalog No.：YT7842
  • Applications：WB;ELISA
  • Reactivity：Human;Rat;Mouse;
    • Target：
    • GROβ
    • Fields：
    • >>Cytokine-cytokine receptor interaction;>>Viral protein interaction with cytokine and cytokine receptor;>>Chemokine signaling pathway;>>NF-kappa B signaling pathway;>>NOD-like receptor signaling pathway;>>IL-17 signaling pathway;>>TNF signaling pathway;>>Alcoholic liver disease;>>Epithelial cell signaling in Helicobacter pylori infection;>>Legionellosis;>>Amoebiasis;>>Kaposi sarcoma-associated herpesvirus infection;>>Rheumatoid arthritis;>>Lipid and atherosclerosis
    • Gene Name：
    • CXCL2 GRO2 GROB MIP2A SCYB2
    • Protein Name：
    • GROβ
    • Human Gene Id：
    • 2920
    • Human Swiss Prot No：
    • P19875
    • Mouse Swiss Prot No：
    • P10889
    • Immunogen：
    • Synthesized peptide derived from human GROβ AA range: 58-107
    • Specificity：
    • This antibody detects endogenous levels of Human GROβ
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • C-X-C motif chemokine 2 (Growth-regulated protein beta;Gro-beta;Macrophage inflammatory protein 2-alpha;MIP2-alpha) [Cleaved into: GRO-beta(5-73;GRO-beta-T;Hematopoietic synergistic factor;HSF;SB-251353)]
    • Molecular Weight(Da)：
    • 12kD
    • Background：
    • function:Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.,online information:CXCL2 entry,pharmaceutical:GRO-beta(5-73) is available under the name Garnocestim as immunomodulator. It is used prior to hematopoietic transplantation for peripheral blood stem cell mobilization and reduction of incidence, duration, and/or severity of chemotherapy induced cytopenias.,PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.,similarity:Belongs to the intercrine alpha (chemokine CxC) family.,
    • Function：
    • chemotaxis, defense response, inflammatory response, immune response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, behavior, locomotory behavior, response to wounding, taxis,
    • Subcellular Location：
    • Secreted.

    Attributes

    • Code：
    • YT7842
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-07-26
    Order

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