A-FABP rabbit pAb
- Catalog No.:YT7833
- Applications:WB;ELISA
- Reactivity:Human;Rat;Mouse;
- Target:
- A-FABP
- Fields:
- >>PPAR signaling pathway;>>Regulation of lipolysis in adipocytes
- Gene Name:
- FABP4
- Protein Name:
- A-FABP
- Human Gene Id:
- 2167
- Human Swiss Prot No:
- P15090
- Mouse Gene Id:
- 11770
- Mouse Swiss Prot No:
- P04117
- Rat Swiss Prot No:
- P70623
- Immunogen:
- Synthesized peptide derived from human A-FABP AA range: 80-120
- Specificity:
- This antibody detects endogenous levels of Human A-FABP
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:1000-2000 ELISA 1:5000-20000
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Fatty acid-binding protein, adipocyte (Adipocyte lipid-binding protein;ALBP;Adipocyte-type fatty acid-binding protein;A-FABP;AFABP;Fatty acid-binding protein 4)
- Molecular Weight(Da):
- 15kD
- Background:
- FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008],
- Function:
- domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,subcellular location:Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.,subunit:Homodimer. Interacts with PPARG (By similarity). Monomer.,
- Subcellular Location:
- Cytoplasm . Nucleus . Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. .
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