TUSC2 Polyclonal Antibody

    • Catalog No.:YT4783
    • Applications:WB;IHC;IF;ELISA
    • Reactivity:Human;Mouse
      • Target:
      • TUSC2
      • Gene Name:
      • TUSC2
      • Protein Name:
      • Tumor suppressor candidate 2
      • Human Swiss Prot No:
      • O75896
      • Mouse Swiss Prot No:
      • Q9WVF8
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human TUSC2. AA range:41-90
      • Specificity:
      • TUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • TUSC2;C3orf11;FUS1;LGCC;PDAP2;Tumor suppressor candidate 2;Fusion 1 protein;Fus-1 protein;PDGFA-associated protein 2
      • Observed Band(KD):
      • 12kD
      • Background:
      • This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],
      • Function:
      • function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,
      • Subcellular Location:
      • mitochondrion,
      • Expression:
      • Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
      • Products Images
      • Western Blot analysis of 293T cells using TUSC2 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
      • Immunohistochemical analysis of paraffin-embedded Human heart. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
      • Western blot analysis of lysates from HeLa cells, using TUSC2 Antibody. The lane on the right is blocked with the synthesized peptide.