TUSC2 Polyclonal Antibody
- Catalog No.:YT4783
- Applications:WB;IHC;IF;ELISA
- Reactivity:Human;Mouse
- Target:
- TUSC2
- Gene Name:
- TUSC2
- Protein Name:
- Tumor suppressor candidate 2
- Human Gene Id:
- 11334
- Human Swiss Prot No:
- O75896
- Mouse Gene Id:
- 80385
- Mouse Swiss Prot No:
- Q9WVF8
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human TUSC2. AA range:41-90
- Specificity:
- TUSC2 Polyclonal Antibody detects endogenous levels of TUSC2 protein.
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
- Purification:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- TUSC2;C3orf11;FUS1;LGCC;PDAP2;Tumor suppressor candidate 2;Fusion 1 protein;Fus-1 protein;PDGFA-associated protein 2
- Observed Band(KD):
- 12kD
- Background:
- This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available. [provided by RefSeq, Jul 2008],
- Function:
- function:May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.,PTM:Myristoylation is required for tumor suppressor activity.,similarity:Belongs to the TUSC2 family.,tissue specificity:Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.,
- Subcellular Location:
- mitochondrion,
- Expression:
- Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta.
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- Antibody-FAQs
- Products Images
- Western Blot analysis of 293T cells using TUSC2 Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded Human heart. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.
- Western blot analysis of lysates from HeLa cells, using TUSC2 Antibody. The lane on the right is blocked with the synthesized peptide.