TM4SF1 Polyclonal Antibody

    • Catalog No.:YT4675
    • Applications:IHC-p,ELISA
    • Reactivity:Human,Mouse
      • Gene Name:
      • TM4SF1
      • Protein Name:
      • Transmembrane 4 L6 family member 1
      • Human Gene Id:
      • 4071
      • Human Swiss Prot No:
      • P30408
      • Mouse Swiss Prot No:
      • Q64302
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human T4S1. AA range:1-50
      • Specificity:
      • TM4SF1 Polyclonal Antibody detects endogenous levels of TM4SF1 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • TM4SF1; M3S1; TAAL6; Transmembrane 4 L6 family member 1; Membrane component chromosome 3 surface marker 1; Tumor-associated antigen L6
      • MolecularWeight(Da):
      • 21632
      • Background:
      • transmembrane 4 L six family member 1(TM4SF1) Homo sapiens The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface antigen and is highly expressed in different carcinomas. [provided by RefSeq, Jul 2008],
      • Function:
      • similarity:Belongs to the L6 tetraspanin family.,subunit:Present in high molecular weight complexes in tumor cells.,tissue specificity:Highly expressed on lung, breast, colon, and ovarian carcinomas. It is also present on some normal cells, endothelial cells in particular.,
      • Subcellular Location:
      • integral component of plasma membrane,integral component of membrane,
      • Expression:
      • Bone marrow,Lung,
      • Products Images
      • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using T4S1 Antibody. The picture on the right is blocked with the synthesized peptide.