• Target：
• Tetraspanin-8

• Gene Name：
• TSPAN8

• Protein Name：
• Tetraspanin-8

• Human Gene Id：
• 7103

• Human Swiss Prot No：
• P19075

• Mouse Swiss Prot No：
• Q8R3G9

• Immunogen：
• The antiserum was produced against synthesized peptide derived from human TSPAN8. AA range:96-145

• Specificity：
• Tetraspanin-8 Polyclonal Antibody detects endogenous levels of Tetraspanin-8 protein.

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

• Purification：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• TSPAN8;TM4SF3;Tetraspanin-8;Tspan-8;Transmembrane 4 superfamily member 3;Tumor-associated antigen CO-029

• Observed Band(KD)：
• 26kD

• Background：
• The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008],

• Function：
• similarity:Belongs to the tetraspanin (TM4SF) family.,tissue specificity:Gastric, colon, rectal, and pancreatic carcinomas.,

• Subcellular Location：
• Membrane; Multi-pass membrane protein.

• Expression：
• Gastric, colon, rectal, and pancreatic carcinomas.

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