SgK288 Polyclonal Antibody

    • Catalog No.:YT4272
    • Applications:WB;ELISA
    • Reactivity:Human;Rat;Mouse;
      • Target:
      • SgK288
      • Gene Name:
      • ANKK1
      • Protein Name:
      • Ankyrin repeat and protein kinase domain-containing protein 1
      • Human Swiss Prot No:
      • Q8NFD2
      • Mouse Swiss Prot No:
      • Q8BZ25
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human ANKK1. AA range:321-370
      • Specificity:
      • SgK288 Polyclonal Antibody detects endogenous levels of SgK288 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Polyclonal, Rabbit,IgG
      • Dilution:
      • WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • ANKK1;PKK2;SGK288;Ankyrin repeat and protein kinase domain-containing protein 1;Protein kinase PKK2;Sugen kinase 288;SgK288;X-kinase
      • Observed Band(KD):
      • 84kD
      • Background:
      • The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009],
      • Function:
      • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 12 ANK repeats.,tissue specificity:Highly expressed in brain and weakly expressed in placenta and spinal cord.,
      • Expression:
      • Highly expressed in brain and weakly expressed in placenta and spinal cord.
      • Products Images
      • Western Blot analysis of various cells using SgK288 Polyclonal Antibody
      • Western blot analysis of lysates from HeLa cells, using ANKK1 Antibody. The lane on the right is blocked with the synthesized peptide.