PDE6G (Phospho Thr22) rabbit pAb

  • Catalog No.:YP1596
  • Applications:WB;ELISA
  • Reactivity:Human;Mouse
    • Target:
    • PDE6G
    • Fields:
    • >>Purine metabolism;>>Metabolic pathways;>>Phototransduction
    • Gene Name:
    • PDE6G PDEG
    • Protein Name:
    • PDE6G (Phospho Thr22)
    • Human Gene Id:
    • 5148
    • Human Swiss Prot No:
    • P18545
    • Mouse Swiss Prot No:
    • P09174
    • Immunogen:
    • Synthesized peptide derived from human PDE6G (Phospho Thr22)
    • Specificity:
    • This antibody detects endogenous levels of Human, Mouse PDE6G (Phospho Thr22)
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Polyclonal, Rabbit,IgG
    • Dilution:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name:
    • Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
    • Observed Band(KD):
    • 69kD
    • Background:
    • This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
    • Function:
    • catalytic activity:Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.,function:Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the rod/cone cGMP-PDE gamma subunit family.,subunit:Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.,