PDE6G (Phospho Thr22) rabbit pAb

  • Catalog No.：YP1596
  • Applications：WB;ELISA
  • Reactivity：Human;Mouse
    • Target：
    • PDE6G
    • Fields：
    • >>Purine metabolism;>>Metabolic pathways;>>Phototransduction
    • Gene Name：
    • PDE6G PDEG
    • Protein Name：
    • PDE6G (Phospho Thr22)
    • Human Gene Id：
    • 5148
    • Human Swiss Prot No：
    • P18545
    • Mouse Swiss Prot No：
    • P09174
    • Immunogen：
    • Synthesized peptide derived from human PDE6G (Phospho Thr22)
    • Specificity：
    • This antibody detects endogenous levels of Human, Mouse PDE6G (Phospho Thr22)
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (GMP-PDE gamma;EC 3.1.4.35)
    • Observed Band(KD)：
    • 69kD
    • Background：
    • This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009],
    • Function：
    • catalytic activity:Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.,function:Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.,online information:Retina International's Scientific Newsletter,similarity:Belongs to the rod/cone cGMP-PDE gamma subunit family.,subunit:Oligomer composed of two catalytic chains (alpha and beta), an inhibitory chain (gamma) and the delta chain.,

    Attributes

    • Code：
    • YP1596
    • Size
    • 50μL / 100μL / 200μL
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-11-25
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