• Target：
• BRSK2

• Gene Name：
• BRSK2 C11orf7 PEN11B SADA STK29 HUSSY-12

• Protein Name：
• BRSK2 (Phospho Thr260)

• Human Gene Id：
• 9024

• Human Swiss Prot No：
• Q8IWQ3

• Mouse Gene Id：
• 75770

• Mouse Swiss Prot No：
• Q69Z98

• Rat Swiss Prot No：
• D3ZML2

• Immunogen：
• Synthesized peptide derived from human BRSK2 (Phospho Thr260)

• Specificity：
• This antibody detects endogenous levels of Human,Mouse,Rat BRSK2 (Phospho Thr260)

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:1000-2000 ELISA 1:5000-20000

• Purification：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Serine/threonine-protein kinase BRSK2 (EC 2.7.11.1;Brain-selective kinase 2;EC 2.7.11.26;Brain-specific serine/threonine-protein kinase 2;BR serine/threonine-protein kinase 2;Serine/threonine-protein kinase 29;Serine/threonine-protein kinase SAD-A)

• Observed Band(KD)：
• 78kD

• Background：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,

• Function：
• catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,

• Subcellular Location：
• Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Endoplasmic reticulum. Detected at centrosomes during mitosis. Localizes to the endoplasmic reticulum in response to stress caused by tunicamycin.

• Expression：
• Detected in pancreas islets (at protein level).

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