S100A6 (ABT179R) rabbit mAb

    • Catalog No.:YM7275
    • Applications:IHC; ELISA
    • Reactivity:Human;
      • Target:
      • S100A6
      • Gene Name:
      • S100A6
      • Protein Name:
      • S100A6
      • Human Gene Id:
      • 6277
      • Human Swiss Prot No:
      • P06703
      • Immunogen:
      • Synthesized peptide derived from human S100A6 AA range:50-90
      • Specificity:
      • This antibody detects endogenous levels of S100A6
      • Formulation:
      • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
      • Source:
      • Monoclonal, Rabbit IgG1, Kappa
      • Dilution:
      • IHC 1:100-500, ELISA 1:5000-20000
      • Purification:
      • Recombinant Expression and Affinity purified
      • Storage Stability:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • Other Name:
      • Protein S100-A6;Calcyclin;Growth factor-inducible protein 2A9;MLN 4;Prolactin receptor-associated protein;PRA;S100 calcium-binding protein A6
      • Background:
      • S100 calcium binding protein A6(S100A6) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008],
      • Function:
      • induction:Preferentially expressed when quiescent fibroblasts are stimulated to proliferate. It is inducible by growth factors and overexpressed in acute myeloid leukemias.,miscellaneous:This protein co-purified with the prolactin receptor.,PTM:The N-terminus is blocked.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer, antiparallel. Interacts with SUGT1.,
      • Subcellular Location:
      • Nuclear, Cytoplasmic
      • Expression:
      • Brain,Fibroblast,Placenta,Platelet,
      • Products Images
      • Immunohistochemical analysis of paraffin-embedded human Pancreatic carcinoma. 1, Antibody was incubated at 4° overnight. 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
      • Immunohistochemical analysis of paraffin-embedded human Papillary thyroid carcinoma. 1, Antibody was incubated at 4° overnight. 2, TRIS-EDTA of pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).