Total eEF2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4079C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • EEF2
    • Human Gene Id:
    • 1938
    • Human Swiss Prot No:
    • P13639
    • Mouse Swiss Prot No:
    • P58252
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Elongation factor 2 (EF-2)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,
    • Function:
    • translation, translational elongation,
    • Subcellular Location:
    • Cytoplasm . Nucleus . Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. .