• Gene Name：
• EEF2

• Human Gene Id：
• 1938

• Human Swiss Prot No：
• P13639

• Mouse Swiss Prot No：
• P58252

• Rat Swiss Prot No：
• P05197

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• Elongation factor 2 (EF-2)

• Detection Method：
• Colorimetric

• Background：
• function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome.,PTM:Diphthamide is 2-[3-carboxyamido-3-(trimethyl-ammonio)propyl]histidine. Diphthamide can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A.,PTM:Phosphorylation by EF-2 kinase completely inactivates EF-2.,similarity:Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.,subunit:Component of the mRNA surveillance SURF complex, at least composed of ERF1, ERF3 (ERF3A or ERF3B), EEF2, UPF1/RENT1, SMG1, SMG8 and SMG9.,

• Function：
• translation, translational elongation,

• Subcellular Location：
• Cytoplasm . Nucleus . Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C-terminal cleavage product. .

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