Total PHCA Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA4231C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- ACER3
- Human Gene Id:
- 55331
- Human Swiss Prot No:
- Q9NUN7
- Mouse Swiss Prot No:
- Q9D099
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Alkaline ceramidase 3 (AlkCDase 3) (Alkaline CDase 3) (EC 3.5.1.-) (Alkaline dihydroceramidase SB89) (Alkaline phytoceramidase) (aPHC)
- Detection Method:
- Colorimetric
- Background:
- enzyme regulation:Activated by Ca(2+) and inhibited by Zn(2+).,function:Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.,similarity:Belongs to the alkaline ceramidase family.,tissue specificity:Ubiquitously expressed. Highest expression in placenta.,
- Function:
- membrane lipid metabolic process, sphingolipid metabolic process, ceramide metabolic process, sphingoid metabolic process,
- Subcellular Location:
- Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
- Expression:
- Ubiquitously expressed. Highly expressed in placenta (PubMed:11356846). Expressed in erythrocytes (PubMed:20207939).
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