Total Ksr2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3796C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • KSR2
    • Human Swiss Prot No:
    • Q6VAB6
    • Mouse Swiss Prot No:
    • Q3UVC0
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Kinase suppressor of Ras 2 (hKSR2)
    • Detection Method:
    • Colorimetric
    • Background:
    • domain:The protein kinase domain is predicted to be catalytically inactive.,function:Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.,PTM:Phosphorylated on Ser-474 by MARK3.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with MAP2K1, MAP3K8, MAPK, RAS and RAF.,tissue specificity:Mainly expressed in brain and kidney.,
    • Function:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, phosphorylation,
    • Subcellular Location:
    • Cytoplasm . Membrane ; Peripheral membrane protein .
    • Expression:
    • Mainly expressed in brain and kidney.