Total LPAAT-θ Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3781C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- AGPAT9
- Human Gene Id:
- 84803
- Human Swiss Prot No:
- Q53EU6
- Mouse Swiss Prot No:
- Q8C0N2
- Rat Swiss Prot No:
- Q4V8J4
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Glycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (Acyl-CoA:glycerol-3-phosphate acyltransferase 3) (hGPAT3) (Lung cancer metastasis-associated protein 1) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta) (MAG-1)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:Acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.,domain:The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.,enzyme regulation:Inhibited by N-ethylmaleimide (NEM).,function:Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Overexpression activates the mTOR pathway.,pathway:Glycerolipid metabolism; triacylglycerol biosynthesis.,pathway:Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3.,similarity:Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.,tissue specificity:Widely expressed. Expressed in liver, kidney, testis, brain, heart, skeletal muscle, thyroid, prostate, thymus and placenta. Also expressed lung and adipose tissue.,
- Function:
- neutral lipid metabolic process, acylglycerol metabolic process, triglyceride metabolic process, phospholipid metabolic process, glycerol ether metabolic process, lipid biosynthetic process, phospholipid biosynthetic process, organic ether metabolic process, triglyceride biosynthetic process, organophosphate metabolic process, regulation of TOR signaling pathway, glycerolipid biosynthetic process, neutral lipid biosynthetic process, acylglycerol biosynthetic process,glycerolipid metabolic process, glycerol ether biosynthetic process,
- Subcellular Location:
- Endoplasmic reticulum membrane ; Multi-pass membrane protein .
- Expression:
- Widely expressed. Expressed in liver, kidney, testis, brain, heart, skeletal muscle, thyroid, prostate, thymus and placenta. Also expressed lung and adipose tissue.
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