Total SURF-1 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3748C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- SURF1
- Human Gene Id:
- 6834
- Human Swiss Prot No:
- Q15526
- Mouse Swiss Prot No:
- P09925
- Rat Swiss Prot No:
- Q9QXU2
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Surfeit locus protein 1
- Detection Method:
- Colorimetric
- Background:
- disease:Defects in SURF1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.,function:Probably involved in the biogenesis of the COX complex.,similarity:Belongs to the SURF1 family.,
- Function:
- generation of precursor metabolites and energy, protein complex assembly, respiratory chain complex IV assembly,aerobic respiration, energy derivation by oxidation of organic compounds, cellular macromolecular complex subunit organization, cellular macromolecular complex assembly, cellular protein complex assembly, macromolecular complex subunit organization, cellular respiration, oxidation reduction, macromolecular complex assembly, protein complex biogenesis,
- Subcellular Location:
- Mitochondrion inner membrane ; Multi-pass membrane protein .
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