Total Dyrk1A Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3723C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • DYRK1A
    • Human Gene Id：
    • 1859
    • Human Swiss Prot No：
    • Q13627
    • Mouse Swiss Prot No：
    • Q61214
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Dual specificity tyrosine-phosphorylation-regulated kinase 1A (EC 2.7.12.1) (Dual specificity YAK1-related kinase) (HP86) (Protein kinase minibrain homolog) (MNBH) (hMNB)
    • Detection Method：
    • Colorimetric
    • Background：
    • alternative products:Additional isoforms seem to exist,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,developmental stage:Expressed in the developing central nervous system.,disease:Overexpressed 1.5-fold in fetal Down syndrome brain.,enzyme regulation:Inhibited by RANBP9.,function:May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates.,PTM:Autophosphorylated on tyrosine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts RAD54L2/ARIP4 (By similarity). Interacts with RANBP9.,tissue specificity:Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney.,
    • Function：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, phosphorylation,peptidyl-tyrosine phosphorylation, peptidyl-tyrosine modification, protein amino acid autophosphorylation,
    • Subcellular Location：
    • Nucleus . Nucleus speckle .
    • Expression：
    • Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney.

    Attributes

    • Code：
    • KA3723C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-07
    Order

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