Total N33 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3713C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • TUSC3
    • Human Gene Id:
    • 7991
    • Human Swiss Prot No:
    • Q13454
    • Mouse Swiss Prot No:
    • Q8BTV1
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:Defects in TUSC3 are the cause of mental retardation non-syndromic autosomal recessive type 7 (MRT7) [MIM:611093]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,function:May be involved in N-glycosylation through its association with N-oligosaccharyl transferase.,similarity:Belongs to the OST3/OST6 family.,subunit:Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B.,tissue specificity:Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.,
    • Function:
    • protein amino acid glycosylation, protein amino acid N-linked glycosylation, glycoprotein metabolic process,glycoprotein biosynthetic process, peptidyl-asparagine modification, protein amino acid N-linked glycosylation via asparagine, biopolymer glycosylation, glycosylation,
    • Subcellular Location:
    • Endoplasmic reticulum membrane ; Multi-pass membrane protein .
    • Expression:
    • Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.