Total ACTR-IB Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3598C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • ACVR1B
    • Human Gene Id：
    • 91
    • Human Swiss Prot No：
    • P36896
    • Mouse Swiss Prot No：
    • Q61271
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.,cofactor:Magnesium or manganese.,function:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Phosphorylates TTRAP.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.,similarity:Contains 1 GS domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with AIP1. Part of a complex consisting of AIP1, ACVR2A, ACVR1B and SMAD3. Interacts with TTRAP.,tissue specificity:Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.,
    • Function：
    • G1/S transition of mitotic cell cycle, mitotic cell cycle, regulation of cell growth, in utero embryonic development, hair follicle development, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, induction of apoptosis, cell cycle, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, ectoderm development, regulation of cell size, epidermis development, embryonic development ending in birth or egg hatching,positive regulation of signal transduction, positive regulation of cell communication, regulation of cell death, positive regulation of cell death, induction of programmed cell death, phosphorylation, peptidyl-threonine phosphorylation,peptidyl-threonine modification, cell cycle process, cell cycle phase, molting cycle proce
    • Subcellular Location：
    • Cell membrane ; Single-pass type I membrane protein .
    • Expression：
    • Expressed in many tissues, most strongly in kidney, pancreas, brain, lung, and liver.

    Attributes

    • Code：
    • KA3598C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-02
    Order

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