Total BCAR3 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3493C
  • Applications：ELISA
  • Reactivity：Human
    • Gene Name：
    • BCAR3
    • Human Gene Id：
    • 8412
    • Human Swiss Prot No：
    • O75815
    • Mouse Swiss Prot No：
    • Q9QZK2
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins.,PTM:Phosphorylated on tyrosine.,similarity:Contains 1 Ras-GEF domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with BCAR1, NEDD9, PTK2 and PTPN1.,tissue specificity:Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.,
    • Function：
    • intracellular signaling cascade, small GTPase mediated signal transduction, response to drug,
    • Subcellular Location：
    • Cytoplasm . Cell junction, focal adhesion . Localization to focal adhesions depends on interaction with PTPRA. .
    • Expression：
    • Ubiquitously expressed. Found in several cancer cell lines, but not in nonmalignant breast tissue.

    Attributes

    • Code：
    • KA3493C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-10
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