Total FAST-1/2 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3491C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- FOXH1
- Human Gene Id:
- 8928
- Human Swiss Prot No:
- O75593
- Mouse Swiss Prot No:
- O88621
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast-1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2)
- Detection Method:
- Colorimetric
- Background:
- domain:The FM region is required for binding smad2/smad4 complexes. FM2 is more effective than FM1 and only interacts with phosphorylated smad2 that is in an activated smad complex.,function:Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Interacts with the MH2 domains of SMAD2 and SMAD3.,tissue specificity:Ubiquitous.,
- Function:
- negative regulation of transcription from RNA polymerase II promoter, regionalization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, transforming growth factor beta receptor signaling pathway,determination of left/right symmetry, pattern specification process, mesoderm development, heart development,determination of symmetry, determination of bilateral symmetry, negative regulation of biosynthetic process, positive regulation of biosynthetic process, anterior/posterior pattern formation, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule meta
- Subcellular Location:
- Nucleus.
- Expression:
- Ubiquitous.
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