Total FAST-1/2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3491C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • FOXH1
    • Human Gene Id:
    • 8928
    • Human Swiss Prot No:
    • O75593
    • Mouse Swiss Prot No:
    • O88621
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Forkhead box protein H1 (Forkhead activin signal transducer 1) (Fast-1) (hFAST-1) (Forkhead activin signal transducer 2) (Fast-2)
    • Detection Method:
    • Colorimetric
    • Background:
    • domain:The FM region is required for binding smad2/smad4 complexes. FM2 is more effective than FM1 and only interacts with phosphorylated smad2 that is in an activated smad complex.,function:Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).,similarity:Contains 1 fork-head DNA-binding domain.,subunit:Interacts with the MH2 domains of SMAD2 and SMAD3.,tissue specificity:Ubiquitous.,
    • Function:
    • negative regulation of transcription from RNA polymerase II promoter, regionalization, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein serine/threonine kinase signaling pathway, transforming growth factor beta receptor signaling pathway,determination of left/right symmetry, pattern specification process, mesoderm development, heart development,determination of symmetry, determination of bilateral symmetry, negative regulation of biosynthetic process, positive regulation of biosynthetic process, anterior/posterior pattern formation, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule meta
    • Subcellular Location:
    • Nucleus.
    • Expression:
    • Ubiquitous.